On May 30. Aehealth Real Time PCR Kit for Monkeypox (MPV) and Multiplex Real time PCR Kit for Monkeypox Virus and Central/West African Clade Typing obtained EU market access through EU approval. Which means Real Time PCR The Kit for Monkeypox (MPV) and the Multiplex Real time PCR Kit for Monkeypox Virus and Central/West African Clade Typing comply with EU regulations and can be sold in EU countries and countries that recognize EU CE certification. On May 29. WHO (World Health Organization) issued a disease information bulletin. From May 13 to 26, 23 non-monkeypox-endemic countries and regions have reported 257 confirmed cases of monkeypox to WHO, and about 120 more. suspected cases. WHO expects more cases of monkeypox to be detected as surveillance is expanded. The virus may have been circulating undetected for weeks or more, with widespread human-to-human transmission. The WHO said that monkey pox constitutes a "moderate risk" to overall public health at global level after cases were reported in countries where the disease is not typically found. Monkeypox is a viral zoonotic disease caused by the monkeypox virus that is capable of transmission between animals and humans, and secondary transmission between humans. Monkeypox viruses share two distinct genetic evolutionary clades - the Central African clade and the West African clade. Among them, the West African clade has a case fatality rate of about 3.6%; the Central African clade has historically caused more severe diseases, with a case fatality rate of about 10.6%, and is considered to be more contagious. The incubation period for monkeypox ranges from 5-21 days, but is usually 6-13 days. During this time, the patient was asymptomatic. Common symptoms include fever, severe headache, swollen lymph nodes, back pain, muscle aches, fatigue, etc. The rash usually begins within 1-3 days after the fever and tends to be more concentrated on the face and extremities rather than the trunk. The rash can affect the face, palms and soles, oral mucosa, genitals, conjunctiva, and cornea. Most infected people recover within a few weeks, but others have died from severe illness. Severe cases are more common in children and are related to the level of exposure to the virus, the patient's health and the nature of the complications, and underlying immunodeficiency may lead to worse outcomes. Complications of monkeypox include secondary infection, bronchopneumonia, sepsis, encephalitis, and corneal infection leading to vision loss. The monkeypox case fatality rate ranges from 0% to 11% in the general population and is higher in children. Aehealth has launched kit for monkeypox virus detection and kit for identifying monkeypox virus clades. The specific gene fragments of monkeypox virus were detected by real-time fluorescent PCR method. which serves as a detection tool in the early confirmation stage of the monkeypox virus. Specific primers and probes are designed based on Monkeypox virus. Assist in accurate diagnosis and prevention of diseases. Aehealth monkeypox PCR kit has high sensitivity to detection serum, lesion exudate and scab. It is contains internal control genes to monitor the whole process of sampling, extraction and amplification. The operation is simple, non-closed equipment required. The test results can be obtained within 30 minutes on conventional instruments at the fastest. Early and rapid diagnosis of suspected infections can effectively control the spread of the disease.Aehealth will continuously pay close attention to global health issues and needs in real time, to help combat the Monkeypox outbreak. Citable reference: World Health Organization (21 May 2022). Disease Outbreak News; Multi-country monkeypox outbreak in non-endemic countries. Available at: https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON385 https://www.cdc.gov/poxvirus/monkeypox/about.html https://www.aehealthgroup.com/monkeypox-virus-and-centralwest-african-clade-typing-product https://www.aehealthgroup.com/mpv-product